⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3311484 | 0.98 | PDPK1 (0.96) | — | |
| SCHEMBL2393815 | 0.98 | PDPK1 (0.96) | — | |
| SCHEMBL348289 | 0.93 | — | — | |
| SCHEMBL18501324 | 0.84 | PDPK1 (0.71) | — | |
| SCHEMBL16253565 | 0.84 | PDPK1 (0.71) | — | |
| SCHEMBL18501325 | 0.84 | PDPK1 (0.71) | — | |
| SCHEMBL24566373 | 0.79 | PDPK1 (0.66) | — | |
| SCHEMBL18501335 | 0.79 | PDPK1 (0.66) | — | |
| SCHEMBL18501334 | 0.79 | PDPK1 (0.66) | — | |
| SCHEMBL16253519 | 0.77 | PDPK1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116550384-B | Preparation method of super-strong fiber supported triazolium salt temperature-sensitive catalyst | 江苏关山度新材料科技有限公司 | 2023-10-13 | — | — | CN | claimed |
| US-20230020329-A1 | Annelated 9-hydroxy-1,8-dioxo-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-7-carboxamides as HIV integrase inhibitors, methods of preparation and application thereof | Ivachtchenko Alexandrovna Alena (US) | 2023-01-19 | — | — | US | claimed |
| WO-2025128777-A1 | INDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF NOD-LIKE RECEPTOR PROTEIN 3 | MERCK SHARP & DOHME LLC (US) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025128781-A1 | AZAINDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF NOD-LIKE RECEPTOR PROTEIN 3 | MERCK SHARP & DOHME LLC (US) | 2025-06-19 | — | — | WO | disclosed |
| US-20240239792-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | ASIA VISION LIMITED (CN) | 2024-07-18 | — | — | US | disclosed |
| US-20240239792-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | ASIA VISION LIMITED (CN) | 2024-07-18 | — | — | US | disclosed |
| CN-111465603-B | Triazolopyridines as gamma secretase modulators | 勃林格殷格翰国际有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-116550384-B | Preparation method of super-strong fiber supported triazolium salt temperature-sensitive catalyst | 江苏关山度新材料科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116550384-B | Preparation method of super-strong fiber supported triazolium salt temperature-sensitive catalyst | 江苏关山度新材料科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| EP-4252755-A2 | THERAPEUTIC COMPOUNDS | C4x Discovery Limited (GB) | 2023-10-04 | — | — | EP | disclosed |
| US-11731974-B2 | N-acyl-(3-substituted)-(8-substituted)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists | OGEDA SA (BE) | 2023-08-22 | — | — | US | disclosed |
| US-7521464-B2 | Pyrazole compounds for treatment of neurodegenerative disorders | PFIZER INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-20080051409-A1 | Indolizine Carboxamides and Aza and Diaza Derivatives Thereof | SCHWARZ PHARMA AG (DE) | 2008-02-28 | — | — | US | disclosed |
| US-20070270474-A1 | drugs have beta-amyloid peptide production inhibitory activity, such as 2-(2-benzo[b]thiophen-4-yl-acetylamino)-N-(5-phenyl-2H-pyrazol-3-yl)-propionamide, useful for treatment of Alzheimer's disease and Down's Syndrome | PFIZER INC. | 2007-11-22 | — | — | US | disclosed |
| US-20070270474-A1 | drugs have beta-amyloid peptide production inhibitory activity, such as 2-(2-benzo[b]thiophen-4-yl-acetylamino)-N-(5-phenyl-2H-pyrazol-3-yl)-propionamide, useful for treatment of Alzheimer's disease and Down's Syndrome | PFIZER INC. | 2007-11-22 | — | — | US | disclosed |
| US-7238721-B2 | Pyrazole compounds for treatment of neurodegenerative disorders | PFIZER INC (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238721-B2 | Pyrazole compounds for treatment of neurodegenerative disorders | PFIZER INC (US) | 2007-07-03 | — | — | US | disclosed |
| US-4325952-A | Method of treating abstinence syndrome with cycloaklyltriazoles | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO (IT) | 1982-04-20 | — | — | US | disclosed |
| US-4307096-A | Method of treating glaucoma with cycloalkyltriazoles | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1981-12-22 | — | — | US | disclosed |
| US-4252721-A | ANTIGLAUCOMIC AND ANTIPSYCHOTIC AGENTS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 1981-02-24 | — | — | US | disclosed |