Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532328 | 1.00 | GSR (0.42) | GSRCYP1A2DPP7DPP4DPP8 | |
| SCHEMBL1173223 | 0.95 | GSR (0.50) | GSRCYP1A2DPP7DPP4DPP8 | |
| SCHEMBL8506702 | 0.95 | GSR (0.41) | GSRCYP1A2DPP7DPP4DPP8 | |
| SCHEMBL1645758 | 0.95 | GSR (0.50) | GSRCYP1A2DPP7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL11573551 | 0.93 | GSR (0.48) | GSRCYP1A2DPP7DPP4DPP8 | |
| Water SCHEMBL6560978 | 0.93 | GSR (0.48) | GSRCYP1A2DPP7DPP4DPP8 | |
| Water SCHEMBL6034325 | 0.93 | GSR (0.48) | GSRCYP1A2DPP7DPP4DPP8 | |
| SCHEMBL28831704 | 0.93 | GSR (0.48) | GSRCYP1A2DPP7DPP4DPP8 | |
| SCHEMBL28831690 | 0.93 | GSR (0.48) | GSRCYP1A2DPP7DPP4DPP8 | |
| SCHEMBL3780217 | 0.92 | GSR (0.45) | GSRCYP1A2DPP7DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831059-B2 | Light chain component of a botulimum toxin, a butyricum toxin, or a tetani toxin; heavy chain translocation component; and a targeting component which selectively binds to a GnRH receptor. | ALLERGAN, INC. | 2004-12-14 | — | — | US | disclosed |
| US-20020177545-A1 | Compositions and methods for treating gonadotrophin related illnesses | ALLERGAN SALES, INC. (US) | 2002-11-28 | — | — | US | disclosed |