Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.61 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486937 | 0.85 | PDGFRB (0.65) | PDGFRBPDGFRARAB9ACYP1A2KDM4E | |
| SCHEMBL31441068 | 0.85 | PDGFRB (0.65) | PDGFRBPDGFRARAB9ACYP1A2KDM4E | |
| SCHEMBL27960103 | 0.79 | PDGFRB (0.67) | PDGFRBPDGFRARAB9ACYP1A2KDM4E | |
| SCHEMBL372292 | 0.78 | PDGFRB (0.71) | PDGFRBPDGFRARAB9ACYP1A2KDM4E | |
| SCHEMBL372291 | 0.78 | PDGFRB (0.71) | PDGFRBPDGFRARAB9ACYP1A2KDM4E | |
| SCHEMBL4814653 | 0.78 | PDGFRB (0.71) | PDGFRBPDGFRARAB9ACYP1A2KDM4E | |
| Formamide SCHEMBL9731556 | 0.77 | PDGFRB (0.56) | PDGFRBPDGFRARAB9ACYP1A2KDM4E | |
| SCHEMBL3084488 | 0.77 | PDGFRB (0.65) | PDGFRBPDGFRARAB9ACYP1A2KDM4E | |
| SCHEMBL7254720 | 0.77 | PDGFRB (0.65) | PDGFRBPDGFRARAB9ACYP1A2KDM4E | |
| SCHEMBL232458 | 0.77 | PDGFRB (0.65) | PDGFRBPDGFRARAB9ACYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6660718-B1 | Grampositive bacteria | MEIJI SEIKA KAISHA, LTD. (JP) | 2003-12-09 | — | — | US | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |
| US-6399582-B1 | GASTROINTESTINAL DISORDERS | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-06-04 | — | — | US | disclosed |
| EP-1191031-A1 | 3-MODIFIED LEUCOMYCIN DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2002-03-27 | — | — | EP | disclosed |