⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882948 | 0.83 | — | — | |
| SCHEMBL11959793 | 0.72 | — | — | |
| SCHEMBL20226853 | 0.72 | — | — | |
| SCHEMBL13909670 | 0.72 | — | — | |
| SCHEMBL14563389 | 0.72 | — | — | |
| SCHEMBL15218470 | 0.72 | — | — | |
| SCHEMBL10259066 | 0.72 | — | — | |
| SCHEMBL19219828 | 0.72 | — | — | |
| SCHEMBL18506487 | 0.72 | — | — | |
| SCHEMBL15195117 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348904-A1 | SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS | BANK OF AMERICA, N.A. | 2023-11-02 | — | — | US | disclosed |
| US-20230134116-A1 | CONJUGATES FOR SELECTIVE RESPONSIVENESS TO VICINAL DIOLS | PROTOMER TECHNOLOGIES, INC. | 2023-05-04 | — | — | US | disclosed |
| WO-2022081911-A1 | LINKER COMPOUNDS COMPRISING AMIDE BONDS | MPEG LA, L.L.C. (US) | 2022-04-21 | — | — | WO | disclosed |
| US-20190202991-A1 | ENERGY CONVERSION DEVICES INCLUDING STABLE IONENES | SIMON FRASER UNIVERSITY (CA) | 2019-07-04 | — | — | US | disclosed |
| US-9890164-B2 | Substituted-quinoxaline-type bridged-piperidine compounds as ORL-1 modulators | PURDUE PHARMA, L.P. (US) | 2018-02-13 | — | — | US | disclosed |
| US-20170216282-A1 | Compounds, Formulations, and Methods for Treating or Preventing Inflammatory Skin Disorders | GALDERMA LABORATORIES INC | 2017-08-03 | — | — | US | disclosed |
| EP-2867255-B1 | METHOD FOR THE SELECTION AND PRODUCTION OF TAILOR-MADE, SELECTIVE AND MULTI-SPECIFIC THERAPEUTIC MOLECULES COMPRISING AT LEAST TWO DIFFERENT TARGETING ENTITIES AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2017-07-19 | — | — | EP | disclosed |
| US-20170182189-A1 | INHIBITING OR DOWNREGULATING GLYCOGEN SYNTHASE BY CREATING PREMATURE STOP CODONS USING ANTISENSE OLIGONUCLEOTIDES | GENZYME CORPORATION | 2017-06-29 | — | — | US | disclosed |
| US-20170186971-A1 | Compound, Light-Emitting Element, Display Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-06-29 | — | — | US | disclosed |
| US-20160380203-A1 | DIBENZOSUBERANE-BASED ELECTRON-TRANSPORT MATERIALS | JENEKHE SAMSON A (US) | 2016-12-29 | — | — | US | disclosed |
| US-20090298878-A1 | OXIME COMPOUNDS AND THE USE THEREOF | PURDUE PHARMA L.P. | 2009-12-03 | — | — | US | disclosed |
| US-7507509-B2 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2009-03-24 | — | — | US | disclosed |
| US-20090060852-A1 | Compounds, Formulations and Methods for Reducing Skin Wrinkles, Creasing and Sagging | GALDERMA LABORATORIES INC. | 2009-03-05 | — | — | US | disclosed |
| US-7491741-B2 | Diaminopropionic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-7439241-B2 | Compounds, formulations, and methods for treating or preventing rosacea | GALDERMA LABORATORIES, INC. (US) | 2008-10-21 | — | — | US | disclosed |
| US-7410975-B2 | Small molecule toll-like receptor (TLR) antagonists | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-08-12 | — | — | US | disclosed |
| US-7354928-B2 | Small molecule inhibitors targeted at Bcl-2 | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-04-08 | — | — | US | disclosed |
| US-20080058322-A1 | Small molecule inhibitors targeted at Bcl-2 | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-03-06 | — | — | US | disclosed |
| US-20070155671-A1 | Diaminopropionic acid derivatives | FOTOUHI NADER | 2007-07-05 | — | — | US | disclosed |
| US-7217728-B2 | Diaminopropionic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2007-05-15 | — | — | US | disclosed |