Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6847491 | 1.00 | NR5A1 (0.42) | NR5A1RARBHTR2AHTR2CHTR1B | |
| SCHEMBL6847400 | 1.00 | NR5A1 (0.42) | NR5A1RARBHTR2AHTR2CHTR1B | |
| SCHEMBL6850146 | 1.00 | NR5A1 (0.42) | NR5A1RARBHTR2AHTR2CHTR1B | |
| SCHEMBL6850360 | 0.90 | RARB (0.39) | NR5A1RARBHTR2AHTR2CHTR1B | |
| SCHEMBL6847301 | 0.90 | RARB (0.39) | NR5A1RARBHTR2AHTR2CHTR1B | |
| SCHEMBL6851567 | 0.90 | RARB (0.39) | NR5A1RARBHTR2AHTR2CHTR1B | |
| SCHEMBL6850426 | 0.90 | RARB (0.39) | NR5A1RARBHTR2AHTR2CHTR1B | |
| SCHEMBL6851458 | 0.90 | RARB (0.39) | NR5A1RARBHTR2AHTR2CHTR1B | |
| SCHEMBL6851858 | 0.90 | PLA2G4B (0.42) | NR5A1RARBHTR2AHTR2CHTR1B | |
| SCHEMBL6851411 | 0.90 | PLA2G4B (0.42) | NR5A1RARBHTR2AHTR2CHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107971-B1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | DESTINY PHARMA LTD (GB) | 2004-11-24 | — | — | EP | disclosed |
| US-6630128-B1 | Insoluble support | DESTINY PHARMA LIMITED (GB) | 2003-10-07 | — | — | US | disclosed |