SCHEMBL6851855

SCHEMBL6851855

COc1ccc(C([O])=O)c(O)c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.75
RAB9A P51151 6/20 0.75
HPGD P15428 4/20 0.72
CYP3A4 P08684 4/20 0.72
MAPK1 P28482 4/20 0.72
ALDH1A1 P00352 4/20 0.72
LMNA P02545 4/20 0.64
CYP2C19 P33261 3/20 0.64
CYP1A2 P05177 2/20 0.64
PGR P06401 2/20 0.64
SLC6A2 P23975 2/20 0.64
ADORA3 P0DMS8 1/20 0.64
AR P10275 1/20 0.64
CHRM1 P11229 1/20 0.64
ALOX15 P16050 1/20 0.64
TBXA2R P21731 1/20 0.64
ADRA1A P35348 1/20 0.64
HIF1A Q16665 1/20 0.64
CYP2D6 P10635 1/20 0.62
PDE4A P27815 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29365072 0.86 NPC1 (1.00) NPC1RAB9AHPGDCYP3A4MAPK1
SCHEMBL1514997 0.86 NPC1 (1.00) NPC1RAB9AHPGDCYP3A4MAPK1
SCHEMBL38652 0.86 NPC1 (1.00) NPC1RAB9AHPGDCYP3A4MAPK1
Paeonol SCHEMBL3710243 0.84 HPGD (1.00) NPC1RAB9AHPGDCYP3A4MAPK1
SCHEMBL29380756 0.84 NPC1 (0.96) NPC1RAB9AHPGDCYP3A4MAPK1
Paeonol SCHEMBL1449478 0.84 HPGD (1.00) NPC1RAB9AHPGDCYP3A4MAPK1
SCHEMBL2526579 0.84 NPC1 (0.96) NPC1RAB9AHPGDCYP3A4MAPK1
SCHEMBL10453973 0.84 NPC1 (0.96) NPC1RAB9AHPGDCYP3A4MAPK1
SCHEMBL6856233 0.84 NPC1 (0.58) NPC1RAB9AHPGDCYP3A4MAPK1
Paeonol SCHEMBL29349833 0.84 HPGD (1.00) NPC1RAB9AHPGDCYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6783913-B2 POLYMERIC ACETAL RESIN CONTAINS UNITS (A), (B), (C), (D), AND (E). UNIT (A) IS A VINYL ALCOHOL UNIT. UNIT; (B) IS A POLYVINYL ACETAL UNIT CONTAINING AN R GROUP, WHERE R IS HYDROGEN, AN ALIPHATIC GROUP, AN AROMATIC GROUP, OR AN KODAK POLYCHROME GRAPHICS LLC 2004-08-31 US claimed
US-20030198887-A1 Polymeric acetal resins containing free radical inhibitors and their use in lithographic printing EASTMAN KODAK COMPANY 2003-10-23 US claimed
EP-1350801-A1 Polymeric acetal resins containing free radical inhibitors and their use in lithographic printing Kodak Polychrome Graphics GmbH (DE) 2003-10-08 EP claimed