Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.42 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 2/20 | 0.40 |
| ▸ | TGM2 | P21980 | 2/20 | 0.40 |
| ▸ | TGM1 | P22735 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212149 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9APDE4BCYP2C19 | |
| SCHEMBL6690204 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9APDE4BCYP2C19 | |
| SCHEMBL6690207 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9APDE4BCYP2C19 | |
| SCHEMBL6690206 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9APDE4BCYP2C19 | |
| SCHEMBL6692868 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9APDE4BCYP2C19 | |
| SCHEMBL6691357 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9APDE4BCYP2C19 | |
| SCHEMBL6696661 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9APDE4BCYP2C19 | |
| SCHEMBL6692864 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9APDE4BCYP2C19 | |
| SCHEMBL6693784 | 0.91 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9APDE4BCYP2C19 | |
| SCHEMBL6694472 | 0.91 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9APDE4BCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1384711-A1 | Optical resolution of a piperidine derivative | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2004-01-28 | — | — | EP | disclosed |