SCHEMBL6852230

SCHEMBL6852230

O[C@H]1C[C@@H](O)[C@H](O)[C@@H](O)C1

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 2/20 0.39
GLA P06280 2/20 0.39
FUCA1 P04066 2/20 0.39
GLB1 P16278 2/20 0.39
CYP2C9 P11712 2/20 0.32
LMNA P02545 2/20 0.32
GAA P10253 1/20 0.32
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10038592 1.00 GBA1 (0.39) GBA1GLAFUCA1GLB1CYP2C9
SCHEMBL19228704 1.00 GBA1 (0.39) GBA1GLAFUCA1GLB1CYP2C9
SCHEMBL14153817 1.00 GBA1 (0.39) GBA1GLAFUCA1GLB1CYP2C9
SCHEMBL22196099 1.00 GBA1 (0.39) GBA1GLAFUCA1GLB1CYP2C9
SCHEMBL18965309 1.00 GBA1 (0.39) GBA1GLAFUCA1GLB1CYP2C9
SCHEMBL24268893 1.00 GBA1 (0.39) GBA1GLAFUCA1GLB1CYP2C9
SCHEMBL1964139 1.00 GBA1 (0.39) GBA1GLAFUCA1GLB1CYP2C9
SCHEMBL16760811 0.96 GBA1 (0.37) GBA1GLAFUCA1GLB1CYP2C9
SCHEMBL20691251 0.93 FUCA1 (0.35) GBA1GLAFUCA1GLB1GAA
SCHEMBL15484275 0.92 FUCA1 (0.39) GBA1GLAFUCA1GLB1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011073492-A1 DERIVATIVES OF AMINOCYCLITOLS, OBTAINMENT PROCEDURE AND USES CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2011-06-23 WO disclosed