Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | IL2 | P60568 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280560 | 0.92 | KDM4E (0.44) | KDM4EHTTALDH1A1LMNAMAPT | |
| SCHEMBL6299778 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9441519 | 0.84 | KDM4E (0.47) | KDM4EHTTATMALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL10561312 | 0.83 | KDM4E (0.46) | KDM4EHTTATMALDH1A1MAPT | |
| SCHEMBL7271916 | 0.82 | KDM4E (0.41) | KDM4EHTTATMALDH1A1LMNA | |
| SCHEMBL420824 | 0.82 | KDM4E (0.38) | KDM4EHTTATMALDH1A1LMNA | |
| SCHEMBL7272559 | 0.80 | KDM4E (0.39) | KDM4EHTTATMALDH1A1LMNA | |
| SCHEMBL7281790 | 0.80 | KDM4E (0.39) | KDM4EHTTATMALDH1A1LMNA | |
| SCHEMBL9677104 | 0.80 | KDM4E (0.46) | KDM4EHTTATMALDH1A1LMNA | |
| SCHEMBL7427164 | 0.79 | KDM4E (0.38) | KDM4EHTTATMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799827-B1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2004-05-12 | — | — | EP | disclosed |
| US-5786486-A | ANTIMICROBIAL, ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0799827-A1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |