Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thioglycolic Acid SCHEMBL1468349 | 1.00 | HMGCR (0.38) | HMGCRCHRM1TBXA2RADRA1ATDP1 | |
| Thioglycolic Acid SCHEMBL98652 | 1.00 | HMGCR (0.38) | HMGCRCHRM1TBXA2RADRA1ATDP1 | |
| Thioglycolic Acid SCHEMBL14645326 | 0.83 | HMGCR (0.38) | HMGCRCHRM1TBXA2RADRA1ATDP1 | |
| Thioglycolic Acid SCHEMBL11585368 | 0.83 | HMGCR (0.38) | HMGCRCHRM1TBXA2RADRA1ATDP1 | |
| Thioglycolic Acid SCHEMBL332611 | 0.83 | HMGCR (0.38) | HMGCRCHRM1TBXA2RADRA1ATDP1 | |
| Glycolic Acid SCHEMBL28570728 | 0.82 | HMGCR (0.41) | HMGCRCHRM1TBXA2RADRA1ATDP1 | |
| Mercaptopropionic Acid SCHEMBL30719339 | 0.82 | ACE (0.46) | KDM4EFFAR3FOLH1LMNA | |
| Mercaptopropionic Acid SCHEMBL999709 | 0.82 | ACE (0.46) | KDM4EFFAR3FOLH1LMNA | |
| Bicarbonate SCHEMBL5187608 | 0.82 | TSHR (0.39) | HMGCRCHRM1TBXA2RADRA1ATDP1 | |
| Succinic Acid SCHEMBL8832713 | 0.80 | EGLN1 (0.53) | HMGCRCHRM1TBXA2RADRA1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777494-B1 | POLYTHIOURETHANE AND POLYTHIOETHER POLYMERS FORMED MAY BE USED ALONE OR MIXED FOR OPTICAL PURPOSES SUCH AS THE MANUFACTURE OF OPHTHALMIC LENSES | OPTIMA INC. | 2004-08-17 | — | — | US | disclosed |
| US-6008296-A | CURABLE MONOMER COMPOSITION COMPRISING A POLYISOCYANATE OR POLYTHIOISOCYANATE, POLYTHIOL, AND POLYENE OF GIVEN FORMULA; NO PHASE SEPERATION, SINGLE GLASS TRANSITION TEMPERATURE, IMPACT RESISTANCE AND HIGH REFRACTIVE INDEX FOR EYEGLASSES | OPTIMA, INC. (US) | 1999-12-28 | — | — | US | disclosed |
| US-5047576-A | Polymerizable vinyl compound having polythioether skeleton | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0284374-A2 | Polymerizable vinyl compound having polythioether skeleton, process for preparation thereof and optical element made therefrom | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1988-09-28 | — | — | EP | disclosed |