SCHEMBL6852864 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	PSEN1	P49768	14/20	0.58

▸	PSEN2	P49810	14/20	0.58

▸	APH1B	Q8WW43	14/20	0.58

▸	NCSTN	Q92542	14/20	0.58

▸	APH1A	Q96BI3	14/20	0.58

▸	PSENEN	Q9NZ42	14/20	0.58

▸	HTR7	P34969	1/20	0.45

▸	KCNH2	Q12809	3/20	0.43

▸	AR	P10275	1/20	0.43

▸	KDM4E	B2RXH2	1/20	0.43

▸	ALDH1A1	P00352	1/20	0.43

▸	CYP3A4	P08684	1/20	0.43

▸	CYP2C9	P11712	1/20	0.43

▸	CYP2C19	P33261	1/20	0.43

▸	USP30	Q70CQ3	1/20	0.43

▸	ROCK2	O75116	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6853736	0.89	PSEN1 (0.56)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6852620	0.87	PSEN1 (0.53)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6852626	0.85	PSEN1 (0.59)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL761094	0.83	PSEN1 (0.65)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6855965	0.83	PSEN1 (0.60)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6855051	0.82	PSEN1 (0.63)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6852563	0.81	PSEN1 (0.60)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6854971	0.81	PSEN1 (0.63)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6853598	0.80	PSEN1 (0.67)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6852561	0.78	PSEN1 (0.57)	PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011059048-A1	NOVEL AMIDE DERIVATIVE	大日本住友製薬株式会社 (JP)	2011-05-19	—	—	WO	disclosed