Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | IL2 | P60568 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272559 | 0.83 | KDM4E (0.39) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL424180 | 0.82 | KDM4E (0.38) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL16508608 | 0.79 | KDM4E (0.51) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL8818334 | 0.79 | ATM (0.49) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL8855987 | 0.78 | KDM4E (0.58) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL7495712 | 0.78 | KDM4E (0.43) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL18380643 | 0.77 | KDM4E (0.61) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL12897084 | 0.77 | KDM4E (0.42) | KDM4EHTTHRH3MAPTLMNA | |
| SCHEMBL668833 | 0.77 | HTT (0.43) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL1535946 | 0.76 | KDM4E (0.51) | KDM4EHTTATMALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799827-B1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2004-05-12 | — | — | EP | disclosed |
| US-5786486-A | ANTIMICROBIAL, ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0799827-A1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |