Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 8/20 | 0.46 |
| ▸ | CDK9 | P50750 | 6/20 | 0.46 |
| ▸ | CDK1 | P06493 | 6/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.46 |
| ▸ | CDK7 | P50613 | 5/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.46 |
| ▸ | CCNH | P51946 | 4/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5999180 | 0.92 | SYK (0.49) | SYKNPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL5998978 | 0.80 | SYK (0.59) | SYKNPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL5998979 | 0.80 | SYK (0.59) | SYKNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL4903303 | 0.68 | ABL1 (0.66) | SYKNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL5732836 | 0.68 | SYK (0.61) | SYKNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL1927060 | 0.68 | ABL1 (0.80) | SYKNPC1RAB9ASMN1; SMN2HPGD | |
| Water SCHEMBL7817247 | 0.67 | SYK (0.59) | SYKNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL19347450 | 0.66 | SYK (1.00) | SYK | |
| SCHEMBL5998636 | 0.66 | SMN1; SMN2 (0.57) | SYKNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL4904236 | 0.66 | ABL1 (0.58) | SYKNPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078682-A2 | CYCLIC COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2004-09-16 | — | — | WO | disclosed |