Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859709 | 0.82 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6852809 | 0.81 | ADORA2A (0.65) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6858354 | 0.80 | ADORA2A (0.55) | ADORA2AADORA1ADORA2BHTTMAPT | |
| SCHEMBL6214522 | 0.80 | ADORA2A (0.71) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2565551 | 0.80 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BHTTHPGD | |
| SCHEMBL6852899 | 0.79 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BKMT2A | |
| SCHEMBL6859505 | 0.79 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2563416 | 0.79 | ADORA2A (0.77) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2563509 | 0.79 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6852717 | 0.79 | ADORA2A (0.56) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787541-B1 | MOVEMENT DISORDERS, PARKINSON'S DISEASE | VERNALIS RESEARCH LIMITED (GB) | 2004-09-07 | — | — | US | disclosed |