Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MITF | O75030 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | F2R | P25116 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | OXTR | P30559 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6748395 | 0.99 | MAPT (0.60) | MAPTKMT2AMITFKDM4EHTT | |
| SCHEMBL6849882 | 0.86 | MAPT (0.52) | MAPTKMT2AMITFKDM4EHTT | |
| Bromide SCHEMBL6748423 | 0.85 | KMT2A (0.54) | MAPTKMT2AMITFKDM4EHTT | |
| Bromide SCHEMBL6750264 | 0.83 | F2R (0.68) | MAPTKMT2AMITFKDM4EHTT | |
| Bromide SCHEMBL6746356 | 0.82 | MAPT (0.59) | MAPTKMT2AMITFKDM4EHTT | |
| Bromide SCHEMBL6750430 | 0.81 | MAPT (0.56) | MAPTKMT2AMITFKDM4EHTT | |
| SCHEMBL23440108 | 0.78 | ATM (0.74) | MAPTKMT2AMITFKDM4EHTT | |
| SCHEMBL14470550 | 0.78 | MAPT (0.88) | MAPTKMT2AMITFKDM4EHTT | |
| Bromide SCHEMBL6748462 | 0.78 | MAPT (0.82) | MAPTKMT2AMITFKDM4EHTT | |
| Bromide SCHEMBL6751209 | 0.77 | KMT2A (0.64) | MAPTKMT2AMITFKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1394152-A1 | 2-IMINOIMIDAZOLE DERIVATIVES (1) | Eisai Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |