Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 9/20 | 0.65 |
| ▸ | HTR3A | P46098 | 6/20 | 0.65 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.65 |
| ▸ | HTR3B | O95264 | 5/20 | 0.65 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.65 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.65 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.65 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6655236 | 1.00 | CHRNA7 (0.65) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6659902 | 1.00 | CHRNA7 (0.65) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6391027 | 0.94 | CHRNA7 (0.58) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| Fumaric Acid SCHEMBL7108375 | 0.94 | CHRNA7 (0.59) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| Fumaric Acid SCHEMBL6846215 | 0.94 | CHRNA7 (0.59) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| Fumaric Acid SCHEMBL6846219 | 0.94 | CHRNA7 (0.59) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| Fumaric Acid SCHEMBL7108368 | 0.94 | CHRNA7 (0.59) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL5917978 | 0.91 | CHRNA7 (0.65) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6660370 | 0.91 | CHRNA7 (0.65) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6389825 | 0.85 | CHRNA7 (0.58) | CHRNA7HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828330-B2 | Central nervous system disorders; schizophrenia; psychological disorders | PHARMACIA & UPJOHN COMPANY | 2004-12-07 | — | — | US | disclosed |