Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22606844 | 1.00 | EPHX1 (0.43) | EPHX1SHBGTP53KDM4EGMNN | |
| SCHEMBL14099623 | 1.00 | EPHX1 (0.43) | EPHX1SHBGTP53KDM4EGMNN | |
| SCHEMBL1020955 | 1.00 | EPHX1 (0.43) | EPHX1SHBGTP53KDM4EGMNN | |
| SCHEMBL3052722 | 1.00 | EPHX1 (0.43) | EPHX1SHBGTP53KDM4EGMNN | |
| SCHEMBL56860 | 1.00 | — | — | |
| SCHEMBL55861 | 1.00 | — | — | |
| SCHEMBL79026 | 1.00 | — | — | |
| SCHEMBL22191947 | 1.00 | EPHX1 (0.43) | EPHX1SHBGTP53KDM4EGMNN | |
| Hydrochloric Acid SCHEMBL5909015 | 0.97 | KDM4E (0.42) | EPHX1SHBGTP53KDM4EGMNN | |
| Hydrochloric Acid SCHEMBL3824601 | 0.97 | KDM4E (0.42) | EPHX1SHBGTP53KDM4EGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780875-B2 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; PSYCHOLOGICAL DISORDERS | SMITHKLINE BEECHAM S.P.A. (IT) | 2004-08-24 | — | — | US | claimed |
| US-6780875-B2 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; PSYCHOLOGICAL DISORDERS | SMITHKLINE BEECHAM S.P.A. (IT) | 2004-08-24 | — | — | US | disclosed |