⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097483 | 0.87 | MEN1 (0.31) | — | |
| SCHEMBL3755180 | 0.84 | — | — | |
| SCHEMBL2495779 | 0.79 | — | — | |
| SCHEMBL29471028 | 0.76 | — | — | |
| SCHEMBL7651773 | 0.73 | — | — | |
| SCHEMBL30141603 | 0.71 | — | — | |
| SCHEMBL3155628 | 0.71 | — | — | |
| SCHEMBL2760826 | 0.69 | — | — | |
| SCHEMBL9564557 | 0.69 | — | — | |
| SCHEMBL30091169 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6830890-B2 | Nucleotide sequences coding peptide for use in the treatment of autoimmune diseases | AFFYMETRIX, INC. | 2004-12-14 | — | — | US | disclosed |
| EP-0604409-B1 | OLIGONUCLEOTIDE ANALOGS FOR DETECTING AND MODULATING RNA ACTIVITY AND GENE EXPRESSION | ISIS PHARMACEUTICALS INC (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-1418179-A2 | Compositions and methods for detecting and modulating rna activity and gene expression | ISIS PHARMACEUTICALS, INC. (US) | 2004-05-12 | — | — | EP | disclosed |
| US-20030049674-A1 | Conformationally-restricted peptide probe libraries | AFFYMETRIX, INC. (US) | 2003-03-13 | — | — | US | disclosed |
| US-6482591-B2 | Libraries of unimolecular, double-stranded oligonucleotides on solid support, useful in screening procedures associated with drug discovery and diagnosis | AFFYMETRIX, INC. | 2002-11-19 | — | — | US | disclosed |
| US-6262241-B1 | ANTISENSE COMPOUNDS WHICH CLEAVE PHOSPHORODIESTER BONDS AND IMPROVE PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES OF OLIGONUCLEOTIDES, USEFUL IN DIAGNOSING DISEASES | ISIS PHARMACEUTICALS, INC. | 2001-07-17 | — | — | US | disclosed |
| US-5948903-A | Synthesis of 3-deazapurines | ISIS PHARMACEUTICALS, INC. (US) | 1999-09-07 | — | — | US | disclosed |
| US-5750692-A | Synthesis of 3-deazapurines | ISIS PHARMACEUTICALS, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5587470-A | 3-deazapurines | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-24 | — | — | US | disclosed |
| US-5457191-A | 3-deazapurines | ISIS PHARMACEUTICALS, INC. (US) | 1995-10-10 | — | — | US | disclosed |