⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10217 | 1.00 | — | — | |
| SCHEMBL10796 | 1.00 | — | — | |
| SCHEMBL3359569 | 1.00 | — | — | |
| Water SCHEMBL27587846 | 0.97 | CA12 (0.42) | — | |
| Ethane SCHEMBL7360363 | 0.97 | CA12 (0.42) | — | |
| Methane SCHEMBL3247537 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL31732955 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL27149835 | 0.97 | — | — | |
| SCHEMBL24086950 | 0.92 | — | — | |
| SCHEMBL15495008 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630562-B2 | Piperidylurea compounds and methods of use thereof | ARCUS BIOSCIENCES, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| EP-4142732-B1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260042777-A1 | PIPERIDYLUREA COMPOUNDS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2026-02-12 | — | — | US | disclosed |
| US-20250270188-A1 | NLRP3 INFLAMMASOME INHIBITORS | NOVARTIS AG (CH) | 2025-08-28 | — | — | US | disclosed |
| CN-119841831-A | Fused heterocyclic NLRP3 inhibitor compound, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2025-04-18 | — | — | CN | disclosed |
| US-20250109122-A1 | CYCLOALKYL PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2025-04-03 | — | — | US | disclosed |
| CN-119732956-A | NLRP3 inflammatory corpuscle inhibitor | 诺华股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-113784957-B | NLRP3 inflammatory corpuscle inhibitor | 诺华股份有限公司 | 2025-02-28 | — | — | CN | disclosed |
| US-12202817-B2 | Cycloalkyl pyrimidines as ferroportin inhibitors | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2025-01-21 | — | — | US | disclosed |
| US-12139471-B2 | NLRP3 inflammasome inhibitors | NOVARTIS AG (CH) | 2024-11-12 | — | — | US | disclosed |
| EP-1831208-A1 | QUATERNARY AMMONIUM SALTS AS M3 ANTAGONISTS | Novartis AG (CH) | 2007-09-12 | — | — | EP | disclosed |
| EP-1377556-B1 | PYRAZOLE DERIVATIVES FOR TREATING HIV | PFIZER LTD (GB) | 2007-04-04 | — | — | EP | disclosed |
| US-20060287362-A1 | Organic compounds | NOVARTIS AG (CH) | 2006-12-21 | — | — | US | disclosed |
| WO-2006112778-A1 | NEW MUSCARINIC RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2006-10-26 | — | — | WO | disclosed |
| CN-1805935-A | Piperidinium and pyrrolidinium derivatives as muscarinic M3 receptor ligands | NORVARTIS AG (CH) | 2006-07-19 | — | — | CN | disclosed |
| WO-2006066929-A1 | QUATERNARY AMMONIUM SALTS AS M3 ANTAGONISTS | NOVARTIS AG (CH) | 2006-06-29 | — | — | WO | disclosed |
| EP-1638940-A2 | PIPERIDINIUM AND PYRROLIDINIUM DERIVATIVES AS LIGANDS FOR THE MUSCARINIC M3 RECEPTOR | Novartis AG (CH) | 2006-03-29 | — | — | EP | disclosed |
| US-20050101595-A1 | N-containing cycloalkyl-substituted amino-thiazole derivatives and pharmaceutical compositions for inhibiting cell proliferation and methods for their use | PFIZER INC. | 2005-05-12 | — | — | US | disclosed |
| WO-2005000815-A2 | PIPERIDINIUM AND PYRROLIDINIUM DERIVATIVES AS LIGANDS FOR THE MUSCARINIC M3 RECEPTOR | NOVARTIS AG (CH) | 2005-01-06 | — | — | WO | disclosed |
| EP-1369414-A1 | Enantiomerically pure Arylcycloalkyl hydroxycarboxylic esters, processes for their preparation and their use as modulators of muscarinic receptors | Noe, Christian R. (AT) | 2003-12-10 | — | — | EP | disclosed |