⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970919 | 0.90 | — | — | |
| SCHEMBL8969389 | 0.87 | — | — | |
| SCHEMBL8969850 | 0.87 | — | — | |
| SCHEMBL3627555 | 0.77 | — | — | |
| SCHEMBL3915910 | 0.76 | — | — | |
| SCHEMBL20390547 | 0.76 | MGAM (0.31) | — | |
| SCHEMBL5674298 | 0.73 | — | — | |
| SCHEMBL31314830 | 0.72 | MGAM (0.33) | — | |
| SCHEMBL4234450 | 0.72 | MGAM (0.33) | — | |
| SCHEMBL12677847 | 0.72 | MGAM (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630719-B2 | Fluorescent acridinium salts, synthesis thereof and use for detection of cardiolipin | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2026-05-19 | — | — | US | disclosed |
| US-20240400529-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF MITOCHONDRIAL DISEASE, INCLUDING FRIEDREICH'S ATAXIA | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-12-05 | — | — | US | disclosed |
| US-20240400588-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF MITOCHONDRIAL DISEASE, INCLUDING FRIEDREICH'S ATAXIA | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-12-05 | — | — | US | disclosed |
| US-20240368098-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF MITOCHONDRIAL DISEASE, INCLUDING FRIEDREICH'S ATAXIA | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-11-07 | — | — | US | disclosed |
| US-12049455-B2 | Compositions and methods for the prevention and/or treatment of mitochondrial disease, including Friedreich's ataxia | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-07-30 | — | — | US | disclosed |
| US-12037350-B2 | Compositions and methods for the prevention and/or treatment of mitochondrial disease, including Friedreich's ataxia | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12037350-B2 | Compositions and methods for the prevention and/or treatment of mitochondrial disease, including Friedreich's ataxia | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-07-16 | — | — | US | disclosed |
| CN-114787287-B | Fluorescent acridine salt, synthesis thereof and application thereof in detection of cardiolipin | 拉脱维亚有机合成学院 | 2024-05-07 | — | — | CN | disclosed |
| EP-4065643-B1 | FLUORESCENT ACRIDINIUM SALTS, SYNTHESIS THEREOF AND USE FOR DETECTION OF CARDIOLIPIN | LATVIAN INST ORGANIC SYNTHESIS (LV) | 2023-12-13 | — | — | EP | disclosed |
| US-20230303506-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF MITOCHONDRIAL DISEASE, INCLUDING FRIEDREICH'S ATAXIA | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-09-28 | — | — | US | disclosed |
| US-6780888-B1 | FAT-SOLUBLE AND STABLE SILICON-CONTAINING DERIVATIVES OF ASCORBIC ACID | L'OREAL S.A. (FR) | 2004-08-24 | — | — | US | disclosed |
| CN-1414967-A | Silicon compounds derived from ascorbic acid, preparation method, composition containing the compounds and application | OREAL (FR) | 2003-04-30 | — | — | CN | disclosed |
| EP-1028120-B1 | Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use | OREAL (FR) | 2003-03-19 | — | — | EP | disclosed |
| US-6221343-B1 | Benzimidazole/benzofuryl-benzazole silicon compounds and UV-photoprotective compositions comprised thereof | SOCIETE L'OREAL S.A. (FR) | 2001-04-24 | — | — | US | disclosed |
| EP-1028120-A1 | Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use | L'OREAL (FR) | 2000-08-16 | — | — | EP | disclosed |
| US-5536732-A | REDUCING INFECTIOUSNESS OF HIV | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-16 | — | — | US | disclosed |
| EP-0454580-B1 | Novel nojirimycin derivatives | MERRELL DOW PHARMA (US) | 1995-12-27 | — | — | EP | disclosed |
| US-5252587-A | Viricides, aids therapy, antidiabetic agent | MERRELL DOW PHARMACEUTICALS, INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0454580-A2 | Novel nojirimycin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-30 | — | — | EP | disclosed |
| EP-0453692-A1 | Novel nojirimycin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-30 | — | — | EP | disclosed |