Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.79 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.64 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.64 |
| ▸ | FAP | Q12884 | 2/20 | 0.64 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10063620 | 1.00 | DPP4 (0.79) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL10063621 | 1.00 | DPP4 (0.79) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL368008 | 0.89 | DPP4 (1.00) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL13316742 | 0.89 | DPP4 (1.00) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL16677087 | 0.83 | DPP4 (0.69) | DPP4DPP8DPP9FAP | |
| SCHEMBL16666716 | 0.83 | DPP4 (0.69) | DPP4DPP8DPP9FAP | |
| SCHEMBL16666714 | 0.83 | DPP4 (0.69) | DPP4DPP8DPP9FAP | |
| SCHEMBL16667518 | 0.83 | DPP4 (0.69) | DPP4DPP8DPP9FAP | |
| SCHEMBL5820943 | 0.83 | DPP4 (0.71) | DPP4DPP8DPP9FAP | |
| SCHEMBL6853064 | 0.82 | DPP4 (0.71) | DPP4DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012022994-A1 | PREPARATION PROCESS OF VILDAGLIPTIN | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2012-02-23 | — | — | WO | disclosed |
| WO-2011042765-A1 | INORGANIC SALT COMPLEXES OF VILDAGLIPTIN | EGIS GYÓGYSZERGYÁR NYILVÁNOSAN MÜKÖDÖ RÉSZVÉNY-TÁRSASÁG (HU) | 2011-04-14 | — | — | WO | disclosed |
| EP-1513519-B1 | THE USE OF SUBSTITUTED CYANOPYRROLIDINES FOR TREATING HYPERLIPIDEMIA | NOVARTIS AG (CH) | 2009-02-18 | — | — | EP | disclosed |