Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 19/20 | 0.60 |
| ▸ | PRKCG | P05129 | 5/20 | 0.60 |
| ▸ | CDK1 | P06493 | 5/20 | 0.60 |
| ▸ | PRKACA | P17612 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.60 |
| ▸ | AKT2 | P31751 | 5/20 | 0.60 |
| ▸ | AKT3 | Q9Y243 | 5/20 | 0.60 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.60 |
| ▸ | PIM1 | P11309 | 3/20 | 0.60 |
| ▸ | KDR | P35968 | 3/20 | 0.60 |
| ▸ | GSK3A | P49840 | 3/20 | 0.60 |
| ▸ | GSK3B | P49841 | 3/20 | 0.60 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.60 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.60 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.60 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.60 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.60 |
| ▸ | PLK4 | O00444 | 2/20 | 0.60 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855369 | 0.92 | AKT1 (0.63) | AKT1PRKCGCDK1PRKACAMAPK1 | |
| SCHEMBL6853159 | 0.89 | AKT1 (0.60) | AKT1PRKCGCDK1PRKACAMAPK1 | |
| SCHEMBL6855283 | 0.87 | AKT1 (0.58) | AKT1PRKCGCDK1PRKACAMAPK1 | |
| SCHEMBL6853466 | 0.86 | AKT1 (0.68) | AKT1PRKCGCDK1PRKACAMAPK1 | |
| SCHEMBL6855300 | 0.84 | AKT1 (0.58) | AKT1PRKCGCDK1PRKACAMAPK1 | |
| SCHEMBL6855296 | 0.84 | AKT1 (0.58) | AKT1PRKCGCDK1PRKACAMAPK1 | |
| SCHEMBL6854922 | 0.84 | AKT1 (0.66) | AKT1PRKCGCDK1PRKACAMAPK1 | |
| SCHEMBL6855642 | 0.82 | AKT1 (0.65) | AKT1PRKCGCDK1PRKACAMAPK1 | |
| SCHEMBL6855648 | 0.82 | AKT1 (0.65) | AKT1PRKCGCDK1PRKACAMAPK1 | |
| SCHEMBL6857705 | 0.80 | AKT1 (0.75) | AKT1PRKCGCDK1PRKACAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831175-B2 | Such as N,N-dimethyl-N-(2-((5-((E)-2-pyridin-4-ylvinyl) pyridin-3-yl)oxy)ethyl)amine | ABBOTT LABORATORIES | 2004-12-14 | — | — | US | claimed |