Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910605 | 0.86 | TSHR (0.42) | ALDH1A1TSHRCA1CA2TDP1 | |
| SCHEMBL17746744 | 0.86 | TSHR (0.42) | ALDH1A1TSHRCA1CA2TDP1 | |
| SCHEMBL4428950 | 0.86 | TSHR (0.42) | ALDH1A1TSHRCA1CA2TDP1 | |
| SCHEMBL8755356 | 0.86 | TSHR (0.42) | ALDH1A1TSHRCA1CA2TDP1 | |
| SCHEMBL5888582 | 0.86 | TSHR (0.42) | ALDH1A1TSHRCA1CA2TDP1 | |
| SCHEMBL25030158 | 0.86 | TSHR (0.42) | ALDH1A1TSHRCA1CA2TDP1 | |
| SCHEMBL933534 | 0.83 | TSHR (0.43) | ALDH1A1TSHRCA1CA2TDP1 | |
| SCHEMBL11505088 | 0.83 | TSHR (0.43) | ALDH1A1TSHRCA1CA2TDP1 | |
| Water SCHEMBL28157926 | 0.80 | TSHR (0.40) | ALDH1A1TSHRCA1CA2TDP1 | |
| SCHEMBL11854466 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004072232-A9 | COVALENT TETHERING OF FUNCTIONAL GROUPS TO PROTEINS | PROMEGA CORP (US) | 2004-10-14 | — | — | WO | disclosed |