Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14151717 | 1.00 | KDM4E (0.49) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19099791 | 0.89 | KDM4E (0.49) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11408928 | 0.83 | CFTR (0.62) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1037866 | 0.81 | SLC6A4 (0.48) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3465672 | 0.81 | SLC6A4 (0.48) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6855637 | 0.81 | SLC6A4 (0.48) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29669002 | 0.81 | SLC6A4 (0.48) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23689573 | 0.81 | CFTR (0.48) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3662428 | 0.81 | CFTR (0.48) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22060305 | 0.81 | CFTR (0.48) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011013644-A1 | SUBSTITUTED PIPERIDINE COMPOUND | 第一三共株式会社 (JP) | 2011-02-03 | — | — | WO | disclosed |