SCHEMBL6855335

SCHEMBL6855335

OC(CN(Cc1cccc(OC(F)(F)F)c1)C1CCCC1)C(F)(F)F

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL993063 0.99 CETP (0.65) CETP
SCHEMBL6858407 0.95 CETP (0.70) CETP
SCHEMBL993642 0.90 CETP (0.63) CETP
SCHEMBL992957 0.90 CETP (0.67) CETP
SCHEMBL993968 0.90 CETP (0.57) CETP
SCHEMBL995559 0.90 CETP (0.59) CETP
SCHEMBL992980 0.87 CETP (0.56) CETP
SCHEMBL992714 0.86 CETP (0.55) CETP
SCHEMBL994090 0.82 CETP (0.60) CETP
SCHEMBL1044888 0.82 CETP (0.63) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6787570-B2 ADMINISTERING AN AROMATIC OR HETEROAROMATIC SUBSTITUTED TERTIARYAMINE COMPOUND TO TREAT ATHEROSCLEROSIS, DYSLIPIDEMIA, AND OTHER CORONARY ARTERY DISEASES PFIZER, INC. 2004-09-07 US claimed