Acetic Acid

SCHEMBL6856161

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nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2A ADRA2B ADRA2C ADRB2 AGTR1 AVPR1A AVPR1B AVPR2 BDKRB2 CALCR CHRNA3 CHRNB4 ESR1 ESR2 GHSR GNRHR GSC1 HSPA8 MALT1 MC1R MC4R NOS1 NOS2 NOS3 OPRK1 OXTR RAMP1 RAMP2 RAMP3 SCN5A SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 dacA dacB dacC folP ftsI mrcA mrcB mrdA rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	CA1	P00915	2/20	0.82

▸	FFAR3	O14843	2/20	0.64

▸	LCK	P06239	1/20	0.64

▸	FYN	P06241	1/20	0.64

▸	CA4	P22748	4/20	0.57

▸	FAHD1	Q6P587	1/20	0.46

▸	LMNA	P02545	3/20	0.42

▸	TSHR	P16473	1/20	0.39

▸	THPO	P40225	1/20	0.39

▸	BLM	P54132	2/20	0.38

▸	MEN1	O00255	1/20	0.38

▸	LDHA	P00338	1/20	0.38

▸	KMT2A	Q03164	1/20	0.38

▸	HDAC3	O15379	1/20	0.37

▸	HDAC1	Q13547	1/20	0.37

▸	HDAC2	Q92769	1/20	0.37

▸	HDAC8	Q9BY41	1/20	0.37

▸	ALOX15	P16050	1/20	0.36

▸	PMP22	Q01453	1/20	0.36

▸	CASP1	P29466	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Acetic Acid SCHEMBL41629	1.00	—	—
Acetic Acid SCHEMBL11533245	1.00	CA1 (0.82)	CA1FFAR3LCKFYNCA4
Acetic Acid SCHEMBL12983374	1.00	CA1 (0.82)	CA1FFAR3LCKFYNCA4
Acetic Acid SCHEMBL6749539	1.00	CA1 (0.82)	CA1FFAR3LCKFYNCA4
Acetic Acid SCHEMBL437034	1.00	CA1 (0.82)	CA1FFAR3LCKFYNCA4
Acetic Acid SCHEMBL11168446	1.00	CA1 (0.82)	CA1FFAR3LCKFYNCA4
Acetic Acid SCHEMBL11171825	1.00	CA1 (0.82)	CA1FFAR3LCKFYNCA4
Acetic Acid SCHEMBL7316954	1.00	CA1 (0.82)	CA1FFAR3LCKFYNCA4
Acetic Acid SCHEMBL10939984	1.00	CA1 (0.82)	CA1FFAR3LCKFYNCA4
Acetic Acid SCHEMBL11177728	1.00	CA1 (0.82)	CA1FFAR3LCKFYNCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1245207-B1	Reusable heat pack	COUNCIL SCIENT IND RES (IN)	2004-11-24	—	—	EP	claimed
US-20020177886-A1	Reusable heat pack, method of manufacture thereof, mixture for use in a reusable heatpack and process for the preparation thereof	COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH	2002-11-28	—	—	US	claimed
WO-2002078584-A1	REUSABLE HEAT PACK	COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN)	2002-10-10	—	—	WO	claimed
EP-1245207-A1	Reusable heat pack	Council of Scientific and Industrial Research (IN)	2002-10-02	—	—	EP	claimed
EP-1245207-B1	Reusable heat pack	COUNCIL SCIENT IND RES (IN)	2004-11-24	—	—	EP	disclosed
US-6537309-B2	Reusable heat pack, method of manufacture thereof, mixture for use in a reusable heatpack and process for the preparation thereof	COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN)	2003-03-25	—	—	US	disclosed
US-20020177886-A1	Reusable heat pack, method of manufacture thereof, mixture for use in a reusable heatpack and process for the preparation thereof	COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH	2002-11-28	—	—	US	disclosed
WO-2002078584-A1	REUSABLE HEAT PACK	COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN)	2002-10-10	—	—	WO	disclosed