Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19510855 | 0.85 | NOTUM (0.44) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL5940278 | 0.81 | NOTUM (0.43) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL25394336 | 0.79 | NOTUM (0.47) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL5940049 | 0.78 | HDAC1 (0.46) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL5940440 | 0.78 | NOTUM (0.62) | CYP4F2CYP4A11MAPTKDM4EMEN1 | |
| SCHEMBL25391342 | 0.78 | NOTUM (0.46) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL19510581 | 0.78 | NOTUM (0.38) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL10130690 | 0.75 | MAPT (0.47) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL5940318 | 0.75 | HDAC1 (0.45) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL5940212 | 0.75 | NOTUM (0.57) | MEN1KMT2AALDH1A1GAANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828159-B1 | Carbopyronine fluorescent dyes | Drexhage, Karl-Heinz (DE) | 2004-12-07 | — | — | US | disclosed |