Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 15/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855434 | 0.93 | AVPR1B (0.55) | AVPR1BHRH3ATM | |
| SCHEMBL6857215 | 0.93 | AVPR1B (0.55) | AVPR1BHRH3ATM | |
| SCHEMBL6857032 | 0.93 | AVPR1B (0.48) | AVPR1BHRH3ATM | |
| SCHEMBL6857187 | 0.90 | AVPR1B (0.49) | AVPR1BHRH3EGFRATM | |
| SCHEMBL6857044 | 0.90 | AVPR1B (0.48) | AVPR1BHRH3 | |
| SCHEMBL6857276 | 0.90 | ATM (0.50) | AVPR1BHRH3EGFRATM | |
| SCHEMBL6855518 | 0.89 | AVPR1B (0.66) | AVPR1BHRH3 | |
| SCHEMBL6857502 | 0.89 | AVPR1B (0.51) | AVPR1BHRH3EGFRATM | |
| SCHEMBL6857248 | 0.88 | AVPR1B (0.55) | AVPR1BEGFR | |
| SCHEMBL6855437 | 0.87 | AVPR1B (0.49) | AVPR1BHRH3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |