Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 7/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6856795 | 0.90 | TRPV1 (0.40) | TRPV1AVPR1BSUCNR1ICMTABL1 | |
| SCHEMBL6856154 | 0.81 | AVPR1B (0.55) | AVPR1BAXL | |
| SCHEMBL6857502 | 0.79 | AVPR1B (0.51) | AVPR1BAXL | |
| SCHEMBL6857370 | 0.78 | TRPV1 (0.39) | TRPV1AVPR1BICMTABL1TRPV3 | |
| SCHEMBL6857380 | 0.78 | TRPV1 (0.38) | TRPV1AVPR1BICMTABL1TRPV3 | |
| SCHEMBL6856761 | 0.76 | AVPR1B (0.41) | TRPV1AVPR1BAXLCNR2 | |
| SCHEMBL6856257 | 0.76 | AVPR1B (0.41) | TRPV1AVPR1BTRPV3CNR2 | |
| SCHEMBL6857005 | 0.72 | AVPR1B (0.55) | AVPR1BAXL | |
| SCHEMBL6857215 | 0.71 | AVPR1B (0.55) | AVPR1BAXL | |
| SCHEMBL6855434 | 0.71 | AVPR1B (0.55) | AVPR1BAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |