⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24816427 | 0.73 | — | — | |
| SCHEMBL9679520 | 0.70 | — | — | |
| SCHEMBL9677675 | 0.70 | — | — | |
| SCHEMBL16705492 | 0.67 | CRBN (0.32) | — | |
| SCHEMBL9678809 | 0.67 | — | — | |
| SCHEMBL13705533 | 0.65 | — | — | |
| SCHEMBL9678649 | 0.63 | CYP3A4 (0.41) | — | |
| SCHEMBL15624085 | 0.62 | — | — | |
| SCHEMBL13995655 | 0.60 | MAPT (0.39) | — | |
| SCHEMBL10178063 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011016501-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR CANCER | 武田薬品工業株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |
| EP-0373542-B1 | IMIDAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1992-06-17 | — | — | EP | disclosed |
| US-4996219-A | Antibody inhibitors | BOEHRINGER MANNHEIM GMBH (DE) | 1991-02-26 | — | — | US | disclosed |
| EP-0373542-A1 | Imidazoline derivatives, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1990-06-20 | — | — | EP | disclosed |