Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1881088 | 0.92 | ADORA2A (0.77) | ADORA1ADORA2A | |
| SCHEMBL1880456 | 0.90 | ADORA2A (0.60) | ADORA1ADORA2A | |
| SCHEMBL1882224 | 0.86 | ADORA2A (0.63) | ADORA1ADORA2A | |
| SCHEMBL1881060 | 0.86 | ADORA1 (0.57) | ADORA1ADORA2A | |
| SCHEMBL1878234 | 0.86 | ADORA2A (0.57) | ADORA1ADORA2A | |
| SCHEMBL1879453 | 0.85 | ADORA2A (0.61) | ADORA1ADORA2A | |
| SCHEMBL1758596 | 0.85 | ADORA1 (0.59) | ADORA1ADORA2A | |
| SCHEMBL12660096 | 0.84 | ADORA2A (0.70) | ADORA1ADORA2A | |
| SCHEMBL1881399 | 0.84 | ADORA2A (0.50) | ADORA1ADORA2A | |
| SCHEMBL1881942 | 0.83 | ADORA2A (0.65) | ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011053509-A1 | ARYL SUBSTITUTED ARYLINDENOPYRIMIDINES AND THEIR USE AS HIGHLY SELECTIVE ADENOSINE A2A RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2011-05-05 | — | — | WO | disclosed |