Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2984542 | 0.82 | PDE3A (0.39) | FGFR1PDE3ALMNACACNA1FALB | |
| SCHEMBL28996805 | 0.82 | PDE3A (0.39) | FGFR1PDE3ALMNACACNA1FALB | |
| SCHEMBL20819437 | 0.81 | PDE3A (0.39) | FGFR1PDE3ALMNACACNA1FALB | |
| SCHEMBL598527 | 0.78 | ABL1 (0.40) | FGFR1PDE3ALMNACACNA1FALB | |
| Phosphoric Acid SCHEMBL20819439 | 0.78 | PDE3A (0.37) | FGFR1PDE3ALMNACACNA1FALB | |
| Phosphoric Acid SCHEMBL20819438 | 0.78 | PDE3A (0.37) | FGFR1PDE3ALMNACACNA1FALB | |
| SCHEMBL29597277 | 0.76 | PDE3A (0.44) | FGFR1PDE3ALMNACACNA1FALB | |
| SCHEMBL9047407 | 0.76 | PDE3A (0.42) | FGFR1PDE3ALMNACACNA1FALB | |
| SCHEMBL31305353 | 0.76 | PDE3A (0.42) | FGFR1PDE3ALMNACACNA1FALB | |
| SCHEMBL10513954 | 0.75 | DDB1 (0.36) | PDE3ALMNACACNA1FALBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787525-B1 | METHOD OF TREATING HIV INFECTIONS AND/OR CANCER DISEASES | SCHOTT HERBERT (DE) | 2004-09-07 | — | — | US | claimed |