Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850305 | 0.83 | MAPT (0.55) | MAPTL3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6850006 | 0.82 | MAPT (0.53) | MAPTL3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6855314 | 0.82 | MAPT (0.54) | MAPTL3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL7532984 | 0.78 | MAPT (0.49) | MAPTL3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6856080 | 0.77 | DPP4 (0.46) | MAPTL3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6853754 | 0.74 | MAPT (0.54) | MAPTL3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6856039 | 0.74 | MAPT (0.55) | MAPTL3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6854190 | 0.73 | MAPT (0.48) | MAPTL3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6855386 | 0.73 | MAPT (0.44) | MAPTL3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL6849975 | 0.73 | MAPT (0.46) | MAPTL3MBTL1ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828315-B1 | Anti- inflammatories, anti-allergics, bronchodilatators, anti-asthmatics, or TNF alpha inhibitors | WARNER-LAMBERT LLC | 2004-12-07 | — | — | US | disclosed |