Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.73 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.73 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212498 | 0.88 | ADORA2A (0.68) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL6217626 | 0.85 | ADORA2A (0.60) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL2561122 | 0.85 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL6859749 | 0.84 | ADORA2A (0.77) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL6852763 | 0.84 | ADORA2A (0.77) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6213678 | 0.84 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6858372 | 0.83 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL6215001 | 0.83 | ADORA2A (0.81) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL2563401 | 0.82 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6216214 | 0.82 | ADORA2A (0.79) | ADORA2AADORA1ADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787541-B1 | MOVEMENT DISORDERS, PARKINSON'S DISEASE | VERNALIS RESEARCH LIMITED (GB) | 2004-09-07 | — | — | US | disclosed |