Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 9/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669307 | 0.92 | CETP (0.35) | CETP | |
| SCHEMBL5669973 | 0.86 | SMYD3 (0.36) | CETPEPHX1SMYD3KMT2AHTT | |
| SCHEMBL5670850 | 0.79 | CETP (0.33) | CETPSMYD3 | |
| SCHEMBL5669750 | 0.78 | CETP (0.32) | CETP | |
| SCHEMBL5669268 | 0.76 | CETP (0.40) | CETP | |
| SCHEMBL6567535 | 0.73 | HTT (0.37) | CETPHTTALDH1A1GAA | |
| SCHEMBL5669311 | 0.73 | CETP (0.41) | CETPEPHX1 | |
| SCHEMBL5669779 | 0.72 | CETP (0.42) | CETPEPHX1 | |
| SCHEMBL7790102 | 0.72 | CETP (0.49) | CETP | |
| SCHEMBL6276333 | 0.72 | CETP (0.48) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787570-B2 | ADMINISTERING AN AROMATIC OR HETEROAROMATIC SUBSTITUTED TERTIARYAMINE COMPOUND TO TREAT ATHEROSCLEROSIS, DYSLIPIDEMIA, AND OTHER CORONARY ARTERY DISEASES | PFIZER, INC. | 2004-09-07 | — | — | US | claimed |