Formaldehyde

Formaldehyde

SCHEMBL6858464

C=O.Nc1ccccc1Cl

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.83
ALDH1A1 P00352 5/20 0.48
NR4A2 P43354 1/20 0.48
CYP3A4 P08684 4/20 0.47
ALOX15 P16050 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
LMNA P02545 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.41
TP53 P04637 1/20 0.40
RECQL P46063 1/20 0.39
PIK3CA P42336 1/20 0.39
ADORA2A P29274 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
PNMT P11086 1/20 0.39
MAPK1 P28482 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25495 0.91
SCHEMBL29472208 0.91
Hydrochloric Acid SCHEMBL4373214 0.88 TSHR (0.94) TSHRALDH1A1NR4A2CYP3A4ALOX15
Hydrochloric Acid SCHEMBL31384191 0.88 TSHR (0.94) TSHRALDH1A1NR4A2CYP3A4ALOX15
Ammonia Solution, Strong SCHEMBL10464135 0.88
SCHEMBL28534574 0.88
Hydrochloric Acid SCHEMBL1819559 0.88
SCHEMBL357039 0.88
Fluoride SCHEMBL23295750 0.86 TSHR (0.88) TSHRALDH1A1NR4A2CYP3A4ALOX15
Nitrogen SCHEMBL29161237 0.86 TSHR (0.88) TSHRALDH1A1NR4A2CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6786155-B2 HYDROPHILIC COATING ON SUBSTRATE, IMAGEABLE COATING ON HYDROPHILIC COATING; HAVING THE SPECIFIED TENSILE PROPERTIES KODAK POLYCHROME GRAPHICS LLC 2004-09-07 US disclosed
US-20030200884-A1 Imagable and imaged members EASTMAN KODAK COMPANY 2003-10-30 US disclosed