Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.34 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480341 | 0.79 | KCNH2 (0.40) | KCNH2CNR1CNR2HRH3TOP2A | |
| SCHEMBL4220873 | 0.74 | — | — | |
| SCHEMBL8646014 | 0.69 | KCNH2 (0.41) | KCNH2NOS2CNR1CNR2HRH3 | |
| SCHEMBL11148828 | 0.68 | KCNH2 (0.44) | CHRM2CHRM3KCNH2CNR1CNR2 | |
| SCHEMBL28843541 | 0.68 | TOP2A (0.40) | TOP2A | |
| SCHEMBL25245113 | 0.68 | KCNH2 (0.34) | KCNH2CNR1CNR2HRH3 | |
| SCHEMBL23153984 | 0.64 | — | — | |
| SCHEMBL24925834 | 0.64 | — | — | |
| SCHEMBL12945953 | 0.63 | — | — | |
| SCHEMBL23402120 | 0.61 | NPC1 (0.37) | KCNH2NOS2CNR1CNR2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1113035-B1 | Polymer and macromolecular solid electrolyte containing the same | NIPPON CATALYTIC CHEM IND (JP) | 2004-04-28 | — | — | EP | disclosed |
| US-6498230-B2 | EXHIBITING HIGH ELECTROCONDUCTIVITY AT LOW TEMPERATURES; EFFICIENCY; FUEL CELLS | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-12-24 | — | — | US | disclosed |
| US-20010020084-A1 | Polymer and macromolecular solid electrolyte containing the same | NIPPON SHOKUBAI CO., LTD. (JP) | 2001-09-06 | — | — | US | disclosed |
| EP-1113035-A2 | Polymer and macromolecular solid electrolyte containing the same | Nippon Shokubai Co., Ltd. (JP) | 2001-07-04 | — | — | EP | disclosed |