Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13269795 | 1.00 | AR (0.36) | ARCYP11B2RAD52XIAPBIRC2 | |
| SCHEMBL3570406 | 1.00 | AR (0.36) | ARCYP11B2RAD52XIAPBIRC2 | |
| SCHEMBL6859327 | 1.00 | AR (0.36) | ARCYP11B2RAD52XIAPBIRC2 | |
| SCHEMBL4597254 | 0.89 | AR (0.38) | ARCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4597253 | 0.89 | AR (0.38) | ARCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3568982 | 0.89 | AR (0.38) | ARCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL23134696 | 0.85 | AR (0.52) | AR | |
| SCHEMBL3565131 | 0.85 | PIM1 (0.37) | ARCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6860724 | 0.85 | PIM1 (0.37) | ARCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3559757 | 0.85 | PARP1 (0.39) | ARCYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040010037-A1 | Cyanophenyl derivative | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2004-01-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010037-A1 | Cyanophenyl derivative | BPHL, AR, KLK3 | AR 2/4885CYP11B2 348/4885RAD52 1741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.