Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668342 | 0.83 | MAPK14 (0.73) | MAPK14 | |
| SCHEMBL6693983 | 0.76 | HDAC6 (0.45) | MAPK14 | |
| SCHEMBL6647374 | 0.72 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL6692396 | 0.72 | MAPK14 (0.57) | MAPK14 | |
| SCHEMBL6669680 | 0.69 | MAPK14 (1.00) | MAPK14MAPK11 | |
| SCHEMBL6668515 | 0.68 | GAA (0.45) | MAPK14 | |
| SCHEMBL6670174 | 0.66 | MAPK14 (0.54) | MAPK14MAPK11 | |
| SCHEMBL6670223 | 0.66 | MAPK14 (0.51) | MAPK14 | |
| SCHEMBL30825422 | 0.66 | PIM1 (0.44) | MAPK14 | |
| SCHEMBL27086241 | 0.66 | PIM1 (0.44) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809199-B2 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES | MERCK & CO., INC. | 2004-10-26 | — | — | US | disclosed |
| US-20030092712-A1 | (Halo-benzo carbonyl)heterocyclo fused phenyl p38 kinase inhibiting agents | MERCK SHARP & DOHME CORP. | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092712-A1 | (Halo-benzo carbonyl)heterocyclo fused phenyl p38 kinase inhibiting agents | MAPK1, MAPK7, MAPKAPK2 | MAPK14 5/4885MAPK11 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.