SCHEMBL6861085

SCHEMBL6861085

CCOC(=O)[CH]C(C)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
ALDH1A1 P00352 2/20 0.37
GLO1 Q04760 1/20 0.36
LMNA P02545 2/20 0.36
HSD17B10 Q99714 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
MAPT P10636 2/20 0.35
ALOX15 P16050 1/20 0.34
SOAT1 P35610 1/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA14 Q9ULX7 2/20 0.33
TSHR P16473 1/20 0.33
CA12 O43570 1/20 0.33
CA7 P43166 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4449178 0.82 HCAR2 (0.43) HCAR2ALDH1A1SMN1; SMN2CA1CA2
SCHEMBL128170 0.78
SCHEMBL7859416 0.74 HCAR2 (0.45) HCAR2NPSR1MGAMGAASI
SCHEMBL1619484 0.71
SCHEMBL10879059 0.71 NPSR1 (0.46) HCAR2NPSR1MGAMGAASI
SCHEMBL10879052 0.71 NPSR1 (0.46) HCAR2NPSR1MGAMGAASI
SCHEMBL9087229 0.70 HCAR2 (0.45) HCAR2NPSR1MGAMGAASI
SCHEMBL2946387 0.70 HCAR2 (0.56) HCAR2NPSR1MGAMGAASI
SCHEMBL2946389 0.70 HCAR2 (0.56) HCAR2NPSR1MGAMGAASI
SCHEMBL6852534 0.69 SMN1; SMN2 (0.46) HCAR2ALDH1A1SMN1; SMN2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6800720-B2 BASE POLYMER CONTAINING AN ESTER GROUP TO BE DECOMPOSED TO A CARBOXYLIC ACID TO BECOME SOLUBLE IN THE DEVELOPER FOR A PHOTORESIST USED IN FINE WORKING OF A SEMICONDUCTOR USING ULTRAVIOLET RAY; HEAT RESISTANCE; OPTICS; ADHESION MITSUI CHEMICALS, INC. (JP) 2004-10-05 US disclosed