Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 7/20 | 0.67 |
| ▸ | INSR | P06213 | 4/20 | 0.67 |
| ▸ | SRC | P12931 | 10/20 | 0.63 |
| ▸ | LCK | P06239 | 5/20 | 0.63 |
| ▸ | TEK | Q02763 | 4/20 | 0.63 |
| ▸ | EGFR | P00533 | 4/20 | 0.63 |
| ▸ | LYN | P07948 | 3/20 | 0.63 |
| ▸ | KDR | P35968 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | RGS12 | O14924 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | GMNN | O75496 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | FYN | P06241 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467053 | 0.88 | LCK (0.81) | INSRSRCLCKTEKEGFR | |
| SCHEMBL6865566 | 0.88 | SRC (0.79) | IGF1RINSRSRCLCKTEK | |
| SCHEMBL6872508 | 0.84 | SRC (0.79) | IGF1RINSRSRCLCKTEK | |
| SCHEMBL6461155 | 0.84 | SRC (0.80) | IGF1RINSRSRCLCKTEK | |
| SCHEMBL6465414 | 0.84 | IGF1R (0.63) | IGF1RINSRSRCLCKTEK | |
| SCHEMBL6461152 | 0.84 | SRC (0.80) | IGF1RINSRSRCLCKTEK | |
| SCHEMBL6467912 | 0.84 | SRC (0.80) | IGF1RINSRSRCLCKTEK | |
| Hydrochloric Acid SCHEMBL8108614 | 0.83 | SRC (0.78) | IGF1RINSRSRCLCKTEK | |
| SCHEMBL6460652 | 0.83 | LCK (0.74) | INSRSRCLCKTEKEGFR | |
| SCHEMBL27555127 | 0.82 | IGF1R (0.56) | IGF1RINSRSRCLCKTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713474-B2 | SERINE-THREONINE AND TYROSINE KINASE INHIBITORS | ABBOTT GMBH & CO. KG (DE) | 2004-03-30 | — | — | US | disclosed |
| US-20030153752-A1 | Pyrrolopyrimidines as therapeutic agents | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153752-A1 | Pyrrolopyrimidines as therapeutic agents | FLT1, FLT4, TFPI | IGF1R 30/4885INSR 1207/4885SRC 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.