Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 11/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847170 | 0.92 | PDK2 (0.42) | PDK2BACE1ALOX5RARBRARG | |
| SCHEMBL5846572 | 0.88 | PDK2 (0.47) | PDK2BACE1ALOX5RARBRARG | |
| SCHEMBL6860685 | 0.86 | PDK2 (0.33) | PDK2BACE1ALOX5TDP2LMNA | |
| SCHEMBL5847178 | 0.86 | PDK2 (0.46) | PDK2BACE1ALOX5RARBRARG | |
| SCHEMBL290998 | 0.83 | PDK2 (0.55) | PDK2ALOX5TDP2MAOAMAOB | |
| SCHEMBL29986604 | 0.83 | PDK2 (0.55) | PDK2ALOX5TDP2MAOAMAOB | |
| SCHEMBL545091 | 0.83 | PDK2 (0.55) | PDK2ALOX5TDP2MAOAMAOB | |
| SCHEMBL6863559 | 0.82 | PDK2 (0.47) | PDK2TDP2RARBRARGRXRA | |
| SCHEMBL6863550 | 0.82 | PDK2 (0.46) | PDK2BACE1ALOX5TDP2MAOA | |
| SCHEMBL6861430 | 0.81 | PDK2 (0.46) | PDK2TDP2RARBRARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0935691-B1 | OPTICAL BRIGHTENING AGENT | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-05-26 | — | — | EP | disclosed |
| US-6187224-B1 | ORGANIC SPIRO COMPOUNDS WHICH COMPRISE A CONJUGATED SYSTEM | AXIVA GMBH (DE) | 2001-02-13 | — | — | US | disclosed |