SCHEMBL6861926

SCHEMBL6861926

C=CCCCCCC[SiH2]CCCCCCCCCCCCCCCCCC

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.73
ALDH1A1 P00352 2/20 0.56
FAAH O00519 2/20 0.37
TRPV1 Q8NER1 1/20 0.37
THRB P10828 1/20 0.36
ABCC4 O15439 1/20 0.35
MAPT P10636 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5968747 0.91 TSHR (0.58) TSHRALDH1A1FAAHTHRB
SCHEMBL7153127 0.85 TSHR (1.00) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL2848855 0.85 TSHR (1.00) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL8746863 0.85 TSHR (1.00) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL1548257 0.85 TSHR (1.00) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL23539923 0.85 TSHR (1.00) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL11900218 0.85 TSHR (1.00) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL22164116 0.85 TSHR (1.00) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL22322880 0.85 TSHR (1.00) TSHRALDH1A1FAAHTRPV1THRB
SCHEMBL11900766 0.85 TSHR (1.00) TSHRALDH1A1FAAHTRPV1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1204149-C Improved olefin polymerization process DOW CHEMICAL CO (US) 2005-06-01 CN disclosed
EP-1054910-B1 IMPROVED OLEFIN POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2004-09-22 EP disclosed
US-6258902-B1 USING A METAL COMPLEX CATALYST AND AN ALKENYL CONTAINING HYDROCARBYLSILANE THE DOW CHEMICAL COMPANY 2001-07-10 US disclosed
EP-1054910-A1 IMPROVED OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 2000-11-29 EP disclosed
WO-1999041289-A1 IMPROVED OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1999-08-19 WO disclosed