Tetrahydrofuran

Tetrahydrofuran

SCHEMBL6862263

C1CCOC1.O=C(O)c1ccc(C(=O)O)c2c1CCCC2

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
FABP4 P15090 7/20 0.39
GFER P55789 1/20 0.39
FABP3 P05413 1/20 0.37
XDH P47989 1/20 0.35
RXRA P19793 3/20 0.35
RXRB P28702 2/20 0.35
RXRG P48443 2/20 0.35
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34
KMO O15229 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4566491 0.92 CYP1A2 (0.48) CYP1A2FABP4GFERFABP3XDH
SCHEMBL87519 0.87 CYP1A2 (0.57) CYP1A2FABP4GFERFABP3XDH
SCHEMBL195800 0.85 CYP1A2 (0.55) CYP1A2FABP4GFERFABP3XDH
SCHEMBL982478 0.85 CYP1A2 (0.55) CYP1A2FABP4GFERFABP3XDH
SCHEMBL3107923 0.85 CYP1A2 (0.55) CYP1A2FABP4GFERFABP3XDH
SCHEMBL3091854 0.85 CYP1A2 (0.55) CYP1A2FABP4GFERFABP3XDH
SCHEMBL2034342 0.85 CYP1A2 (0.55) CYP1A2FABP4GFERFABP3XDH
Cyclohexane SCHEMBL1538047 0.85 CYP1A2 (0.55) CYP1A2FABP4GFERFABP3XDH
SCHEMBL250454 0.85 CYP1A2 (0.55) CYP1A2FABP4GFERFABP3XDH
Terephthalic Acid SCHEMBL2839189 0.85 TSHR (0.44) CYP1A2RXRARXRBRXRGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0976854-B1 Monofilamentary bicomponent core-sheath fibres TEIJIN MONOFILAMENT GER GMBH (DE) 2004-11-10 EP claimed
US-6254987-B1 CORE IS A LIQUID CRYSTALLINE POLYESTER AND THE SHEATH IS A BLEND OF 1-5 PERCENT BY WEIGHT POLYCARBONATE AND A POLYESTER; DISPLAYS ENHANCED ABRASION RESISTANCE. JOHNS MANVILLE INTERNATIONAL, INC. 2001-07-03 US disclosed