Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13136817 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL3057358 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL13136808 | 0.88 | HDAC1 (0.52) | HDAC1HDAC6 | |
| SCHEMBL3060050 | 0.88 | HDAC1 (0.52) | HDAC1HDAC6 | |
| SCHEMBL12317364 | 0.88 | HDAC1 (0.52) | HDAC1HDAC6 | |
| SCHEMBL13178014 | 0.88 | AKR1C3 (0.55) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL13136814 | 0.86 | HDAC6 (0.53) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL3040480 | 0.86 | HDAC6 (0.53) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL6864353 | 0.85 | HDAC1 (0.51) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL8242490 | 0.84 | HDAC1 (0.59) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007054776-A9 | STILBENE LIKE COMPOUNDS AS NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-03-03 | — | — | WO | disclosed |