Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29716387 | 0.96 | GAA (0.36) | POLBAPEX1HTTTDP1GAA | |
| SCHEMBL3880166 | 0.96 | GAA (0.36) | POLBAPEX1HTTTDP1GAA | |
| SCHEMBL110871 | 0.92 | GAA (0.37) | POLBGAAMEN1KMT2ANPC1 | |
| SCHEMBL29384951 | 0.92 | GAA (0.37) | POLBGAAMEN1KMT2ANPC1 | |
| SCHEMBL13228157 | 0.89 | GAA (0.39) | HTTTDP1GAAMEN1KMT2A | |
| SCHEMBL29404702 | 0.87 | POLB (0.38) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL93349 | 0.87 | POLB (0.38) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL21925041 | 0.87 | NPC1 (0.38) | POLBGAAMEN1KMT2ANPC1 | |
| SCHEMBL17701294 | 0.87 | GAA (0.34) | POLBHTTGAAMEN1KMT2A | |
| SCHEMBL14213069 | 0.87 | NPC1 (0.34) | POLBAPEX1HTTTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144496-B1 | POLYMERIC STABILIZERS HAVING LOW POLYDISPERSITY | CIBA SC HOLDING AG (CH) | 2004-03-17 | — | — | EP | disclosed |
| US-6583245-B1 | Ethylenically unsaturated compound (acrylate or acrylamide) having sterically hindered amine, hydroxyphenyl triazine, hydroxyphenylbenzotriazole or a o-hydroxy-benzophenone group; a nitroxyl free radical initiator | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-24 | — | — | US | disclosed |
| EP-1144496-A1 | POLYMERIC STABILIZERS HAVING LOW POLYDISPERSITY | Ciba SC Holding AG (CH) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000039209-A1 | POLYMERIC STABILIZERS HAVING LOW POLYDISPERSITY | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-07-06 | — | — | WO | disclosed |