Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867491 | 0.89 | ADORA2A (0.47) | ADORA2A | |
| SCHEMBL6870499 | 0.85 | ADORA2A (0.59) | ADORA2AHPGD | |
| SCHEMBL6871231 | 0.85 | ADORA2A (0.45) | ADORA2AHPGDNPSR1 | |
| SCHEMBL6867741 | 0.84 | ADORA2A (0.46) | ADORA2AHPGD | |
| SCHEMBL6871350 | 0.82 | ADORA2A (0.41) | ADORA2A | |
| SCHEMBL6871970 | 0.81 | ADORA2A (0.43) | ADORA2AHPGD | |
| SCHEMBL6867399 | 0.79 | ADORA2A (0.67) | ADORA2AHPGD | |
| SCHEMBL6869056 | 0.78 | ADORA2A (0.66) | ADORA2AHPGD | |
| SCHEMBL6870464 | 0.77 | ADORA2A (0.42) | ADORA2A | |
| SCHEMBL6870459 | 0.77 | ADORA2A (0.43) | ADORA2AHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |