Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 17/20 | 0.64 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870601 | 0.92 | ADORA2A (0.65) | ADORA2AALDH1A1 | |
| SCHEMBL6871702 | 0.90 | ADORA2A (0.77) | ADORA2A | |
| SCHEMBL6873982 | 0.89 | ADORA2A (0.81) | ADORA2A | |
| SCHEMBL6867105 | 0.83 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL6869682 | 0.81 | ADORA2A (0.62) | ADORA2A | |
| SCHEMBL6872091 | 0.81 | ADORA2A (0.82) | ADORA2A | |
| SCHEMBL6869719 | 0.81 | ADORA2A (0.61) | ADORA2A | |
| SCHEMBL6866841 | 0.80 | ADORA2A (0.55) | ADORA2AF2ALDH1A1USP2 | |
| SCHEMBL6863123 | 0.80 | ADORA2A (0.60) | ADORA2A | |
| SCHEMBL6871980 | 0.79 | ADORA2A (0.79) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |