Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 18/20 | 0.67 |
| ▸ | CETP | P11597 | 1/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6872781 | 0.83 | TACR1 (0.74) | TACR1GPBAR1 | |
| SCHEMBL5779738 | 0.82 | TACR1 (0.59) | TACR1GPBAR1 | |
| SCHEMBL5781646 | 0.81 | TACR1 (0.54) | TACR1GPBAR1 | |
| SCHEMBL6872779 | 0.80 | TACR1 (1.00) | TACR1 | |
| SCHEMBL6871449 | 0.79 | TACR1 (0.55) | TACR1GPBAR1 | |
| SCHEMBL6016603 | 0.79 | TACR1 (0.50) | TACR1CETPGPBAR1 | |
| SCHEMBL5763724 | 0.78 | TACR1 (0.61) | TACR1GPBAR1 | |
| SCHEMBL6016671 | 0.78 | TACR1 (0.49) | TACR1CETPGPBAR1 | |
| SCHEMBL5781165 | 0.77 | TACR1 (0.49) | TACR1GPBAR1 | |
| SCHEMBL8785556 | 0.77 | TACR1 (0.73) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171419-B1 | BIPHENYL DERIVATIVES AS ANTAGONISTS OF THE NEUROKININE-1 RECEPTOR | HOFFMANN LA ROCHE (CH) | 2004-12-29 | — | — | EP | claimed |