Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 2/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870881 | 1.00 | CYP4F2 (0.42) | CYP4F2CYP4A11MAPTEPHX1HSPD1 | |
| SCHEMBL6871551 | 1.00 | CYP4F2 (0.42) | CYP4F2CYP4A11MAPTEPHX1HSPD1 | |
| SCHEMBL6872504 | 1.00 | CYP4F2 (0.42) | CYP4F2CYP4A11MAPTEPHX1HSPD1 | |
| SCHEMBL6872030 | 1.00 | CYP4F2 (0.42) | CYP4F2CYP4A11MAPTEPHX1HSPD1 | |
| SCHEMBL6874398 | 1.00 | CYP4F2 (0.42) | CYP4F2CYP4A11MAPTEPHX1HSPD1 | |
| SCHEMBL6873143 | 1.00 | CYP4F2 (0.42) | CYP4F2CYP4A11MAPTEPHX1HSPD1 | |
| SCHEMBL6870852 | 1.00 | CYP4F2 (0.42) | CYP4F2CYP4A11MAPTEPHX1HSPD1 | |
| SCHEMBL6870440 | 0.99 | CYP4F2 (0.43) | CYP4F2CYP4A11MAPTEPHX1HSPD1 | |
| SCHEMBL6863449 | 0.94 | CYP4F2 (0.41) | CYP4F2CYP4A11MAPTEPHX1HSPD1 | |
| SCHEMBL2455719 | 0.89 | MAPT (0.42) | CYP4F2CYP4A11MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379522-A1 | DIHYDRO-BENZO(b)(1,4)DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS I | F. HOFFMANN-LA ROCHE AG (CH) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002083665-A1 | DIHYDRO-BENZO[b][1,4]DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS I | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-24 | — | — | WO | disclosed |